MF1 Respirology Objectives

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Objectives Linked ActivitiesMcMaster Program Competencies

General Objectives

Describe the normal physiology and anatomy (where appropriate) as applied to each respirology theme (Drive to breathe; Respiratory pump and mechanics of breathing; Airflow obstruction; Lung defences, injury and inflammation; Gas exchange).

Tutorial: All MF1 Respirology tutorial problems
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Describe the mechanism of disease (pathophysiology, pathology) as applied to each respirology theme (Drive to breathe; Respiratory pump and mechanics of breathing; Airflow obstruction; Lung defences, injury and inflammation; Gas exchange)

Tutorial: All MF1 Respirology tutorial problems
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Explain the possible mechanisms responsible for the symptoms described by the patient: dyspnea, cough, wheeze, sputum production.

Tutorial: All MF1 Respirology tutorial problems
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Conduct an appropriate respiratory history, including medication and occupation history.

Clinical Skills Sessions: Respiratory Exam: Practice Case – Dyspnea & Wheeze
Discuss and practice the components of the respiratory history and physical examination. Practice an approach to the environmental exposure history using the CH2 OPD2 format. Pro-Comp Connection – Health Effects of Climate Change: : Climate change presents a fundamental threat to human health, with the potential to undermine and reverse decades of health progress. Increasingly frequent disruptions caused by climate change may overwhelm the efforts of the healthcare system to address social determinants of health, if those latter efforts ignore the changing environment. Climate change impacts health both directly and indirectly and is strongly mediated by structural determinants of health.
Tutorial: Arthur N. MF1 Respirology
Arthur N., a 64-year-old gentleman, presents to his family physician because he is noticing increasing difficulty walking because of breathlessness. He states that he cannot put a finger on when it first began "except that he is aware that he was not as fit" as he should be. Arthur has always enjoyed his walking. However, over the last six months, he has noticed that any incline will make him breathless to the point that friends will remark on it, and he simply has to stop walking. In addition, climbing stairs has become quite difficult. He remarks that he has not been breathless at rest, nor at night-time. He has not noticed any swelling of his ankles. Arthur states that he smoked lightly about twenty years ago. His occupational history is unremarkable and there is no history of heart disease.
1.1 Gather essential and accurate information about patients and their health through history-taking, physical examination, and the use of laboratory data, imaging, and other tests.
4.1 Communicate effectively with patients, families, and the public, as appropriate, across a broad range of socioeconomic and sociocultural backgrounds
4.4 Demonstrate insight and understanding about emotions and human responses to emotions that allow one to develop and manage interpersonal interactions, including the ability to manage one’s own interpersonal responses
5.2 Demonstrate compassion, integrity, and respect for others
5.4 Demonstrate respect for patient confidentiality, privacy and autonomy

Conduct an appropriate physical exam of the respiratory system.

Clinical Skills Sessions: Respiratory Exam: Practice Case – Dyspnea & Wheeze
Discuss and practice the components of the respiratory history and physical examination. Practice an approach to the environmental exposure history using the CH2 OPD2 format. Pro-Comp Connection – Health Effects of Climate Change: : Climate change presents a fundamental threat to human health, with the potential to undermine and reverse decades of health progress. Increasingly frequent disruptions caused by climate change may overwhelm the efforts of the healthcare system to address social determinants of health, if those latter efforts ignore the changing environment. Climate change impacts health both directly and indirectly and is strongly mediated by structural determinants of health.
1.1 Gather essential and accurate information about patients and their health through history-taking, physical examination, and the use of laboratory data, imaging, and other tests.

Develop an approach to diagnostic tests as applied to the respiratory system: arterial blood gases, pulmonary function tests, chest x-rays, exercise testing.

Active Large Group Session: Approach to Pulmonary Function Tests
What are Pulmonary Function Tests? Noninvasive measure of lung volume, capacity, flow rates and gas exchange.
Active Large Group Session: Approach to the chest x-ray
Active Large Group Session: Introduction to ABGs
1.3 Interpret laboratory data, imaging studies, and other tests required for the area of practice
2.3 Apply principles of clinical sciences to diagnostic and therapeutic decision-making, clinical problem-solving, and other aspects of evidence-based healthcare

Develop an approach to management of respiratory diseases: medications (including oxygen), behavioural modifications and population measures for prevention.

Tutorial: John Fumer MF1 Respirology
John Fumer is a 54 year old man who began smoking at the age of 14 and has averaged a pack a day since then. Five years ago, he noticed that heavy exertion such as climbing 2 flights of stairs would leave him more "winded" than usual but there was no major impact on his lifestyle (including smoking!) Over the last 18 months, he has noticed increasing restriction on his activities. When a friend pointed out that he could no longer "walk and talk at the same time", he decided to seek help from his family physician.
1.1 Gather essential and accurate information about patients and their health through history-taking, physical examination, and the use of laboratory data, imaging, and other tests.
1.3 Interpret laboratory data, imaging studies, and other tests required for the area of practice
1.4 Make informed decision about diagnostic and therapeutic interventions based on patient information and preferences, up-to-date scientific evidence, and clinical judgment
2.3 Apply principles of clinical sciences to diagnostic and therapeutic decision-making, clinical problem-solving, and other aspects of evidence-based healthcare
2.4 Apply principles of epidemiological sciences to the identification of health problems, risk factors, treatment strategies, resource allocation, and disease prevention/health promotion efforts for patients and populations
2.5 Apply principles of socio-behavioural sciences to the provision of patient care, including assessment of the impact of psychosocial and cultural influences on health, disease, care-seeking, care concordance, care adherence and barriers to and attitudes toward care.
6.2 Identify aspects of the healthcare system that serve as barriers and enablers of providing healthcare to and optimizing the health of patients and the population

Themes

Drive to Breathe

Describe the factors that govern respiratory drive under normal circumstances, including central and peripheral controls.

Tutorial: T. Petty MF1 Respirology
A youth is brought into the emergency department by paramedics after being found unconscious lying on a sewer grate. No further history is available. In the triage unit, the patient’s respiratory rate is 8 breaths per minute, and breaths are shallow. Heart rate is 50 beats per minute. Oxygen saturation by pulse oximetry is 90% on room air. Pupils are constricted and fixed. “Track marks” are noted on the forearms. The triage nurse applies oxygen by mask and the emergency resident orders a medication given through an intravenous line. Three minutes later the patient is awake, agitated, and complaining of severe generalized pain. Respiratory rate is 30 breaths per minute. When the medicine resident arrives at the bedside an hour later to admit the patient, the youth is once more unconscious, breathing slowly and shallowly as on arrival in triage.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Explain the impact of hyper- or hypoventilation on arterial blood gas balance.

Tutorial: Teresa J. MF1 Respirology
Teresa, a 65-year-old woman, is brought to the emergency room by a friend who was unable to arouse Teresa completely. Her friend reports that Teresa had been unwell for three days with persistent vomiting. In the emergency room, Teresa is only semi-rousable. Her pulse is 130 and blood pressure is 100/70. Her breathing is rapid and deep. Teresa’s medical record indicates a history of poorly controlled diabetes and premature coronary artery disease, with a prior myocardial infarction at age 49. She is described as “treatment non-compliant” and is noted to have a “difficult psychosocial situation”.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Recognize some of the common clinical situations where alteration in drive to breathe is manifested: altitude, intentional or anxiety driven hyperventilation, chronic CO2 retention in COPD, sleep apnea, and opiate use.

Tutorial: Sarah Rosenthal MF1 Respirology
Sarah Rosenthal, a 63-year-old woman, has been a smoker for many years and has noticed a gradual reduction in her exercise tolerance over the last three years, finding it more difficult to garden and to walk to her synagogue. She has been able to modify her activities in response to the limitations imposed by her breathlessness but her family has noted her weight has been increasing. When her family noticed that her legs were becoming more swollen and that she was not as "sharp" as usual, they decided to bring her to the emergency room. Her family reports that Sarah has recently visited her family physician and was prescribed a diuretic for her ankle swelling.
Tutorial: T. Petty MF1 Respirology
A youth is brought into the emergency department by paramedics after being found unconscious lying on a sewer grate. No further history is available. In the triage unit, the patient’s respiratory rate is 8 breaths per minute, and breaths are shallow. Heart rate is 50 beats per minute. Oxygen saturation by pulse oximetry is 90% on room air. Pupils are constricted and fixed. “Track marks” are noted on the forearms. The triage nurse applies oxygen by mask and the emergency resident orders a medication given through an intravenous line. Three minutes later the patient is awake, agitated, and complaining of severe generalized pain. Respiratory rate is 30 breaths per minute. When the medicine resident arrives at the bedside an hour later to admit the patient, the youth is once more unconscious, breathing slowly and shallowly as on arrival in triage.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Explain the physiological response of the body (heart, lungs and blood) to increased demand for oxygen during exercise and at high altitudes.

Tutorial: Sarah Rosenthal MF1 Respirology
Sarah Rosenthal, a 63-year-old woman, has been a smoker for many years and has noticed a gradual reduction in her exercise tolerance over the last three years, finding it more difficult to garden and to walk to her synagogue. She has been able to modify her activities in response to the limitations imposed by her breathlessness but her family has noted her weight has been increasing. When her family noticed that her legs were becoming more swollen and that she was not as "sharp" as usual, they decided to bring her to the emergency room. Her family reports that Sarah has recently visited her family physician and was prescribed a diuretic for her ankle swelling.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Respiratory Pump and Mechanics of Breathing

Explain the normal mechanics of lung inflation and deflation, including the role of intrapleural pressure in inflation of the lung and the role of tissue elasticity and surface tension in elastic recoil of the lung.

Tutorial: Rana Osman MF1 Respirology
Rana Osman is a 2-year-old girl who has been previously well. She has had a barky, seal-like cough for 2 days but tonight has become acutely worse. In the emergency room, she is found to be sitting "bolt upright", with pronounced stridor on inspiration. Her inspiratory phase is prolonged. She has intercostal indrawing and suprasternal indrawing.
Tutorial: Ron Chen MF1 Respirology
Ron Chen is a 25 year old computer sciences post-graduate student who had been previously well. Three weeks ago he suffered a viral gastroenteritis from which he has recovered. Over the past week, he has noticed increasing weakness of his limbs, starting with his legs, and progressing to involve his arms. He reports he has experienced patchy areas of sensory loss, symmetrically. He has also noticed occasional clumsy speech and facial weakness.
Tutorial: T. Petty MF1 Respirology
A youth is brought into the emergency department by paramedics after being found unconscious lying on a sewer grate. No further history is available. In the triage unit, the patient’s respiratory rate is 8 breaths per minute, and breaths are shallow. Heart rate is 50 beats per minute. Oxygen saturation by pulse oximetry is 90% on room air. Pupils are constricted and fixed. “Track marks” are noted on the forearms. The triage nurse applies oxygen by mask and the emergency resident orders a medication given through an intravenous line. Three minutes later the patient is awake, agitated, and complaining of severe generalized pain. Respiratory rate is 30 breaths per minute. When the medicine resident arrives at the bedside an hour later to admit the patient, the youth is once more unconscious, breathing slowly and shallowly as on arrival in triage.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Identify the lung volumes that can be measured during spirometry and full pulmonary function.

Tutorial: Arthur N. MF1 Respirology
Arthur N., a 64-year-old gentleman, presents to his family physician because he is noticing increasing difficulty walking because of breathlessness. He states that he cannot put a finger on when it first began "except that he is aware that he was not as fit" as he should be. Arthur has always enjoyed his walking. However, over the last six months, he has noticed that any incline will make him breathless to the point that friends will remark on it, and he simply has to stop walking. In addition, climbing stairs has become quite difficult. He remarks that he has not been breathless at rest, nor at night-time. He has not noticed any swelling of his ankles. Arthur states that he smoked lightly about twenty years ago. His occupational history is unremarkable and there is no history of heart disease.
Tutorial: John Fumer MF1 Respirology
John Fumer is a 54 year old man who began smoking at the age of 14 and has averaged a pack a day since then. Five years ago, he noticed that heavy exertion such as climbing 2 flights of stairs would leave him more "winded" than usual but there was no major impact on his lifestyle (including smoking!) Over the last 18 months, he has noticed increasing restriction on his activities. When a friend pointed out that he could no longer "walk and talk at the same time", he decided to seek help from his family physician.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Explain the pathophysiology of some of the common disease processes affecting the respiratory pump (upper airway, neuromusculature, lower airways and lung parenchyma).

Tutorial: Ron Chen MF1 Respirology
Ron Chen is a 25 year old computer sciences post-graduate student who had been previously well. Three weeks ago he suffered a viral gastroenteritis from which he has recovered. Over the past week, he has noticed increasing weakness of his limbs, starting with his legs, and progressing to involve his arms. He reports he has experienced patchy areas of sensory loss, symmetrically. He has also noticed occasional clumsy speech and facial weakness.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Describe how the mechanics of breathing are disturbed in examples of obstructive and non-obstructive (“restrictive”) diseases.

Tutorial: Arthur N. MF1 Respirology
Arthur N., a 64-year-old gentleman, presents to his family physician because he is noticing increasing difficulty walking because of breathlessness. He states that he cannot put a finger on when it first began "except that he is aware that he was not as fit" as he should be. Arthur has always enjoyed his walking. However, over the last six months, he has noticed that any incline will make him breathless to the point that friends will remark on it, and he simply has to stop walking. In addition, climbing stairs has become quite difficult. He remarks that he has not been breathless at rest, nor at night-time. He has not noticed any swelling of his ankles. Arthur states that he smoked lightly about twenty years ago. His occupational history is unremarkable and there is no history of heart disease.
Tutorial: John Fumer MF1 Respirology
John Fumer is a 54 year old man who began smoking at the age of 14 and has averaged a pack a day since then. Five years ago, he noticed that heavy exertion such as climbing 2 flights of stairs would leave him more "winded" than usual but there was no major impact on his lifestyle (including smoking!) Over the last 18 months, he has noticed increasing restriction on his activities. When a friend pointed out that he could no longer "walk and talk at the same time", he decided to seek help from his family physician.
Tutorial: Ron Chen MF1 Respirology
Ron Chen is a 25 year old computer sciences post-graduate student who had been previously well. Three weeks ago he suffered a viral gastroenteritis from which he has recovered. Over the past week, he has noticed increasing weakness of his limbs, starting with his legs, and progressing to involve his arms. He reports he has experienced patchy areas of sensory loss, symmetrically. He has also noticed occasional clumsy speech and facial weakness.
Tutorial: Thomas Gagnon MF1 Respirology
Thomas Gagnon, a 12 year old boy diagnosed with asthma 1 year ago, traditionally experienced minimal respiratory symptoms. In the past, he had used inhaled salbutamol sparingly, generally during soccer games, with excellent therapeutic effect. During a late September soccer game being held in a rural area, Thomas developed sudden onset dyspnea, wheeze, and chest discomfort. Earlier in the day he had visited with family members who smoke and have three pet cats. His symptoms were mostly relieved with repeated doses of salbutamol. He awakes the following night with ongoing symptoms that are not responsive to inhaled salbutamol, despite frequent dosing. His parents are alarmed and take him to the emergency department.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Explain the assessment of respiratory pump failure using diagnostic tests.

Tutorial: Ron Chen MF1 Respirology
Ron Chen is a 25 year old computer sciences post-graduate student who had been previously well. Three weeks ago he suffered a viral gastroenteritis from which he has recovered. Over the past week, he has noticed increasing weakness of his limbs, starting with his legs, and progressing to involve his arms. He reports he has experienced patchy areas of sensory loss, symmetrically. He has also noticed occasional clumsy speech and facial weakness.
1.3 Interpret laboratory data, imaging studies, and other tests required for the area of practice

Develop a mechanism-based approach to management of respiratory pump failure.

Tutorial: Ron Chen MF1 Respirology
Ron Chen is a 25 year old computer sciences post-graduate student who had been previously well. Three weeks ago he suffered a viral gastroenteritis from which he has recovered. Over the past week, he has noticed increasing weakness of his limbs, starting with his legs, and progressing to involve his arms. He reports he has experienced patchy areas of sensory loss, symmetrically. He has also noticed occasional clumsy speech and facial weakness.
1.1 Gather essential and accurate information about patients and their health through history-taking, physical examination, and the use of laboratory data, imaging, and other tests.
1.3 Interpret laboratory data, imaging studies, and other tests required for the area of practice
1.4 Make informed decision about diagnostic and therapeutic interventions based on patient information and preferences, up-to-date scientific evidence, and clinical judgment
2.3 Apply principles of clinical sciences to diagnostic and therapeutic decision-making, clinical problem-solving, and other aspects of evidence-based healthcare

Airflow Obstruction

Describe the factors that determine airway calibre (upper and lower), including autonomic control and chemical mediators of inflammation.

Active Large Group Session: Introduction to Immunology
Tutorial: Edwin McKenzie MF1 Respirology
Edwin is a 4-year-old boy enjoying a day at the Caledonia Fall Fair. He is walking around, enjoying the sights while eating a hot dog, when he suddenly begins to choke. Bystanders look on, horrified. An alert medical student, who happens to be taking a break from studying, is on the scene. She rushes over, comes up behind Edwin and administers an abdominal thrust. The piece of hot dog is expelled from Edwin, and he takes a big breath.He is fine, the medical student is relieved and congratulations are offered all around at this happy ending. In speaking with Edwin’s parents after the incident, the medical student notices a colorful circular pin on his mother’s jacket. The medical student inquires about the pin, and Edwin’s mother states the pin represents the Medicine Wheel, an important concept for their family’s health.
Tutorial: Rana Osman MF1 Respirology
Rana Osman is a 2-year-old girl who has been previously well. She has had a barky, seal-like cough for 2 days but tonight has become acutely worse. In the emergency room, she is found to be sitting "bolt upright", with pronounced stridor on inspiration. Her inspiratory phase is prolonged. She has intercostal indrawing and suprasternal indrawing.
Tutorial: Thomas Gagnon MF1 Respirology
Thomas Gagnon, a 12 year old boy diagnosed with asthma 1 year ago, traditionally experienced minimal respiratory symptoms. In the past, he had used inhaled salbutamol sparingly, generally during soccer games, with excellent therapeutic effect. During a late September soccer game being held in a rural area, Thomas developed sudden onset dyspnea, wheeze, and chest discomfort. Earlier in the day he had visited with family members who smoke and have three pet cats. His symptoms were mostly relieved with repeated doses of salbutamol. He awakes the following night with ongoing symptoms that are not responsive to inhaled salbutamol, despite frequent dosing. His parents are alarmed and take him to the emergency department.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Explain the basic pathophysiology of the diseases which result in airway obstruction (upper and lower airway).

Tutorial: Edwin McKenzie MF1 Respirology
Edwin is a 4-year-old boy enjoying a day at the Caledonia Fall Fair. He is walking around, enjoying the sights while eating a hot dog, when he suddenly begins to choke. Bystanders look on, horrified. An alert medical student, who happens to be taking a break from studying, is on the scene. She rushes over, comes up behind Edwin and administers an abdominal thrust. The piece of hot dog is expelled from Edwin, and he takes a big breath.He is fine, the medical student is relieved and congratulations are offered all around at this happy ending. In speaking with Edwin’s parents after the incident, the medical student notices a colorful circular pin on his mother’s jacket. The medical student inquires about the pin, and Edwin’s mother states the pin represents the Medicine Wheel, an important concept for their family’s health.
Tutorial: John Fumer MF1 Respirology
John Fumer is a 54 year old man who began smoking at the age of 14 and has averaged a pack a day since then. Five years ago, he noticed that heavy exertion such as climbing 2 flights of stairs would leave him more "winded" than usual but there was no major impact on his lifestyle (including smoking!) Over the last 18 months, he has noticed increasing restriction on his activities. When a friend pointed out that he could no longer "walk and talk at the same time", he decided to seek help from his family physician.
Tutorial: Rana Osman MF1 Respirology
Rana Osman is a 2-year-old girl who has been previously well. She has had a barky, seal-like cough for 2 days but tonight has become acutely worse. In the emergency room, she is found to be sitting "bolt upright", with pronounced stridor on inspiration. Her inspiratory phase is prolonged. She has intercostal indrawing and suprasternal indrawing.
Tutorial: Thomas Gagnon MF1 Respirology
Thomas Gagnon, a 12 year old boy diagnosed with asthma 1 year ago, traditionally experienced minimal respiratory symptoms. In the past, he had used inhaled salbutamol sparingly, generally during soccer games, with excellent therapeutic effect. During a late September soccer game being held in a rural area, Thomas developed sudden onset dyspnea, wheeze, and chest discomfort. Earlier in the day he had visited with family members who smoke and have three pet cats. His symptoms were mostly relieved with repeated doses of salbutamol. He awakes the following night with ongoing symptoms that are not responsive to inhaled salbutamol, despite frequent dosing. His parents are alarmed and take him to the emergency department.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Explain the effects of airflow obstruction on the respiratory tract, lung mechanics and gas exchange. Use this knowledge to explain the symptoms and signs with which the patient with lower or upper airway obstruction presents.

Tutorial: Edwin McKenzie MF1 Respirology
Edwin is a 4-year-old boy enjoying a day at the Caledonia Fall Fair. He is walking around, enjoying the sights while eating a hot dog, when he suddenly begins to choke. Bystanders look on, horrified. An alert medical student, who happens to be taking a break from studying, is on the scene. She rushes over, comes up behind Edwin and administers an abdominal thrust. The piece of hot dog is expelled from Edwin, and he takes a big breath.He is fine, the medical student is relieved and congratulations are offered all around at this happy ending. In speaking with Edwin’s parents after the incident, the medical student notices a colorful circular pin on his mother’s jacket. The medical student inquires about the pin, and Edwin’s mother states the pin represents the Medicine Wheel, an important concept for their family’s health.
Tutorial: John Fumer MF1 Respirology
John Fumer is a 54 year old man who began smoking at the age of 14 and has averaged a pack a day since then. Five years ago, he noticed that heavy exertion such as climbing 2 flights of stairs would leave him more "winded" than usual but there was no major impact on his lifestyle (including smoking!) Over the last 18 months, he has noticed increasing restriction on his activities. When a friend pointed out that he could no longer "walk and talk at the same time", he decided to seek help from his family physician.
Tutorial: Rana Osman MF1 Respirology
Rana Osman is a 2-year-old girl who has been previously well. She has had a barky, seal-like cough for 2 days but tonight has become acutely worse. In the emergency room, she is found to be sitting "bolt upright", with pronounced stridor on inspiration. Her inspiratory phase is prolonged. She has intercostal indrawing and suprasternal indrawing.
Tutorial: Thomas Gagnon MF1 Respirology
Thomas Gagnon, a 12 year old boy diagnosed with asthma 1 year ago, traditionally experienced minimal respiratory symptoms. In the past, he had used inhaled salbutamol sparingly, generally during soccer games, with excellent therapeutic effect. During a late September soccer game being held in a rural area, Thomas developed sudden onset dyspnea, wheeze, and chest discomfort. Earlier in the day he had visited with family members who smoke and have three pet cats. His symptoms were mostly relieved with repeated doses of salbutamol. He awakes the following night with ongoing symptoms that are not responsive to inhaled salbutamol, despite frequent dosing. His parents are alarmed and take him to the emergency department.
1.1 Gather essential and accurate information about patients and their health through history-taking, physical examination, and the use of laboratory data, imaging, and other tests.
1.3 Interpret laboratory data, imaging studies, and other tests required for the area of practice
1.4 Make informed decision about diagnostic and therapeutic interventions based on patient information and preferences, up-to-date scientific evidence, and clinical judgment
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.
2.3 Apply principles of clinical sciences to diagnostic and therapeutic decision-making, clinical problem-solving, and other aspects of evidence-based healthcare

Explain the assessment of airflow obstruction using diagnostic tests.

Tutorial: John Fumer MF1 Respirology
John Fumer is a 54 year old man who began smoking at the age of 14 and has averaged a pack a day since then. Five years ago, he noticed that heavy exertion such as climbing 2 flights of stairs would leave him more "winded" than usual but there was no major impact on his lifestyle (including smoking!) Over the last 18 months, he has noticed increasing restriction on his activities. When a friend pointed out that he could no longer "walk and talk at the same time", he decided to seek help from his family physician.
Tutorial: Thomas Gagnon MF1 Respirology
Thomas Gagnon, a 12 year old boy diagnosed with asthma 1 year ago, traditionally experienced minimal respiratory symptoms. In the past, he had used inhaled salbutamol sparingly, generally during soccer games, with excellent therapeutic effect. During a late September soccer game being held in a rural area, Thomas developed sudden onset dyspnea, wheeze, and chest discomfort. Earlier in the day he had visited with family members who smoke and have three pet cats. His symptoms were mostly relieved with repeated doses of salbutamol. He awakes the following night with ongoing symptoms that are not responsive to inhaled salbutamol, despite frequent dosing. His parents are alarmed and take him to the emergency department.
1.3 Interpret laboratory data, imaging studies, and other tests required for the area of practice

Develop a mechanism-based approach to management of airflow obstruction.

Tutorial: Thomas Gagnon MF1 Respirology
Thomas Gagnon, a 12 year old boy diagnosed with asthma 1 year ago, traditionally experienced minimal respiratory symptoms. In the past, he had used inhaled salbutamol sparingly, generally during soccer games, with excellent therapeutic effect. During a late September soccer game being held in a rural area, Thomas developed sudden onset dyspnea, wheeze, and chest discomfort. Earlier in the day he had visited with family members who smoke and have three pet cats. His symptoms were mostly relieved with repeated doses of salbutamol. He awakes the following night with ongoing symptoms that are not responsive to inhaled salbutamol, despite frequent dosing. His parents are alarmed and take him to the emergency department.
1.1 Gather essential and accurate information about patients and their health through history-taking, physical examination, and the use of laboratory data, imaging, and other tests.
1.3 Interpret laboratory data, imaging studies, and other tests required for the area of practice
1.4 Make informed decision about diagnostic and therapeutic interventions based on patient information and preferences, up-to-date scientific evidence, and clinical judgment
2.3 Apply principles of clinical sciences to diagnostic and therapeutic decision-making, clinical problem-solving, and other aspects of evidence-based healthcare

Lung Defences, Injury and Inflammation

Describe the acute response of the respiratory system to inhaled material.

Tutorial: Edwin McKenzie MF1 Respirology
Edwin is a 4-year-old boy enjoying a day at the Caledonia Fall Fair. He is walking around, enjoying the sights while eating a hot dog, when he suddenly begins to choke. Bystanders look on, horrified. An alert medical student, who happens to be taking a break from studying, is on the scene. She rushes over, comes up behind Edwin and administers an abdominal thrust. The piece of hot dog is expelled from Edwin, and he takes a big breath.He is fine, the medical student is relieved and congratulations are offered all around at this happy ending. In speaking with Edwin’s parents after the incident, the medical student notices a colorful circular pin on his mother’s jacket. The medical student inquires about the pin, and Edwin’s mother states the pin represents the Medicine Wheel, an important concept for their family’s health.
Tutorial: Luke Tomczak MF1 Respirology
Luke, a 47 year old gentleman with a history of chronic alcoholism and poor eating habits, goes to the ER with a complaint of chest pain. He smokes two packs of cigarettes daily. He has not been feeling well for over one week due to an upper respiratory infection. Two days ago he developed a fever, chills and a sharp pain over his right chest that is worse when he breathes in. Luke had a dry cough initially, but today he has coughed up rusty sputum with some blood in it. Although Luke is not normally short of breath, he has had difficulty climbing the stairs to the office because of breathlessness.
Tutorial: Nabil Assad MF1 Respirology
Salim takes Nabil, his 7-year-old son, to see Dr. Lockwood, his family doctor, because both of them have a sore throat. Nabil’s younger brother had a sore throat and runny nose a week ago, but he improved quickly. Salim is concerned about Nabil because he seems to be taking longer to improve. Dr. Lockwood asks more details and learns that both Nabil and Salim are mostly having swallowing difficulties but feel otherwise quite well. Salim has a mild cough, but Nabil does not. There have been no rigors, just slight chills last night.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Describe the response of the respiratory system to chronic inflammation.

Active Large Group Session: Introduction to Immunology
Tutorial: Arthur N. MF1 Respirology
Arthur N., a 64-year-old gentleman, presents to his family physician because he is noticing increasing difficulty walking because of breathlessness. He states that he cannot put a finger on when it first began "except that he is aware that he was not as fit" as he should be. Arthur has always enjoyed his walking. However, over the last six months, he has noticed that any incline will make him breathless to the point that friends will remark on it, and he simply has to stop walking. In addition, climbing stairs has become quite difficult. He remarks that he has not been breathless at rest, nor at night-time. He has not noticed any swelling of his ankles. Arthur states that he smoked lightly about twenty years ago. His occupational history is unremarkable and there is no history of heart disease.
Tutorial: Luke Tomczak MF1 Respirology
Luke, a 47 year old gentleman with a history of chronic alcoholism and poor eating habits, goes to the ER with a complaint of chest pain. He smokes two packs of cigarettes daily. He has not been feeling well for over one week due to an upper respiratory infection. Two days ago he developed a fever, chills and a sharp pain over his right chest that is worse when he breathes in. Luke had a dry cough initially, but today he has coughed up rusty sputum with some blood in it. Although Luke is not normally short of breath, he has had difficulty climbing the stairs to the office because of breathlessness.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Describe the main respiratory pathogens in community and hospital-acquired lung infections along with their major distinguishing features.

Tutorial: Luke Tomczak MF1 Respirology
Luke, a 47 year old gentleman with a history of chronic alcoholism and poor eating habits, goes to the ER with a complaint of chest pain. He smokes two packs of cigarettes daily. He has not been feeling well for over one week due to an upper respiratory infection. Two days ago he developed a fever, chills and a sharp pain over his right chest that is worse when he breathes in. Luke had a dry cough initially, but today he has coughed up rusty sputum with some blood in it. Although Luke is not normally short of breath, he has had difficulty climbing the stairs to the office because of breathlessness.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Recognize the importance of occupational exposures leading to respiratory disease.

Tutorial: Arthur N. MF1 Respirology
Arthur N., a 64-year-old gentleman, presents to his family physician because he is noticing increasing difficulty walking because of breathlessness. He states that he cannot put a finger on when it first began "except that he is aware that he was not as fit" as he should be. Arthur has always enjoyed his walking. However, over the last six months, he has noticed that any incline will make him breathless to the point that friends will remark on it, and he simply has to stop walking. In addition, climbing stairs has become quite difficult. He remarks that he has not been breathless at rest, nor at night-time. He has not noticed any swelling of his ankles. Arthur states that he smoked lightly about twenty years ago. His occupational history is unremarkable and there is no history of heart disease.
Tutorial: John Fumer MF1 Respirology
John Fumer is a 54 year old man who began smoking at the age of 14 and has averaged a pack a day since then. Five years ago, he noticed that heavy exertion such as climbing 2 flights of stairs would leave him more "winded" than usual but there was no major impact on his lifestyle (including smoking!) Over the last 18 months, he has noticed increasing restriction on his activities. When a friend pointed out that he could no longer "walk and talk at the same time", he decided to seek help from his family physician.
2.4 Apply principles of epidemiological sciences to the identification of health problems, risk factors, treatment strategies, resource allocation, and disease prevention/health promotion efforts for patients and populations

Discuss the concept underlying Adult Respiratory Distress Syndrome (ARDS) and some of its most common causes.

Tutorial: Teresa J. MF1 Respirology
Teresa, a 65-year-old woman, is brought to the emergency room by a friend who was unable to arouse Teresa completely. Her friend reports that Teresa had been unwell for three days with persistent vomiting. In the emergency room, Teresa is only semi-rousable. Her pulse is 130 and blood pressure is 100/70. Her breathing is rapid and deep. Teresa’s medical record indicates a history of poorly controlled diabetes and premature coronary artery disease, with a prior myocardial infarction at age 49. She is described as “treatment non-compliant” and is noted to have a “difficult psychosocial situation”.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Gas Exchange

Explain the relationship between alveolar ventilation, gas exchange and the acid-base balance in the blood.

Tutorial: John Fumer MF1 Respirology
John Fumer is a 54 year old man who began smoking at the age of 14 and has averaged a pack a day since then. Five years ago, he noticed that heavy exertion such as climbing 2 flights of stairs would leave him more "winded" than usual but there was no major impact on his lifestyle (including smoking!) Over the last 18 months, he has noticed increasing restriction on his activities. When a friend pointed out that he could no longer "walk and talk at the same time", he decided to seek help from his family physician.
Tutorial: Teresa J. MF1 Respirology
Teresa, a 65-year-old woman, is brought to the emergency room by a friend who was unable to arouse Teresa completely. Her friend reports that Teresa had been unwell for three days with persistent vomiting. In the emergency room, Teresa is only semi-rousable. Her pulse is 130 and blood pressure is 100/70. Her breathing is rapid and deep. Teresa’s medical record indicates a history of poorly controlled diabetes and premature coronary artery disease, with a prior myocardial infarction at age 49. She is described as “treatment non-compliant” and is noted to have a “difficult psychosocial situation”.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Describe the oxyhemoglobin and CO2 dissociation curves.

2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Explain the effect of the distribution of ventilation and perfusion within the lungs on gas exchange, and what is meant by the terms "shunt" and "dead space"

Tutorial: Arthur N. MF1 Respirology
Arthur N., a 64-year-old gentleman, presents to his family physician because he is noticing increasing difficulty walking because of breathlessness. He states that he cannot put a finger on when it first began "except that he is aware that he was not as fit" as he should be. Arthur has always enjoyed his walking. However, over the last six months, he has noticed that any incline will make him breathless to the point that friends will remark on it, and he simply has to stop walking. In addition, climbing stairs has become quite difficult. He remarks that he has not been breathless at rest, nor at night-time. He has not noticed any swelling of his ankles. Arthur states that he smoked lightly about twenty years ago. His occupational history is unremarkable and there is no history of heart disease.
Tutorial: Devi Gopal MF1 Respirology
A 55 year-old lady is reviewed in the Respirology clinic because she has become increasingly breathless and can no longer keep up with her friends when walking. The referral letter notes that she has no history of heart disease. She denies any cough, wheezing, or chest pain. She does say that she spends a lot of her time lying down in bed because this eases her breathlessness.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Explain the basic pathophysiology of the diseases which result in disturbances in gas exchange.

Tutorial: Arthur N. MF1 Respirology
Arthur N., a 64-year-old gentleman, presents to his family physician because he is noticing increasing difficulty walking because of breathlessness. He states that he cannot put a finger on when it first began "except that he is aware that he was not as fit" as he should be. Arthur has always enjoyed his walking. However, over the last six months, he has noticed that any incline will make him breathless to the point that friends will remark on it, and he simply has to stop walking. In addition, climbing stairs has become quite difficult. He remarks that he has not been breathless at rest, nor at night-time. He has not noticed any swelling of his ankles. Arthur states that he smoked lightly about twenty years ago. His occupational history is unremarkable and there is no history of heart disease.
Tutorial: Teresa J. MF1 Respirology
Teresa, a 65-year-old woman, is brought to the emergency room by a friend who was unable to arouse Teresa completely. Her friend reports that Teresa had been unwell for three days with persistent vomiting. In the emergency room, Teresa is only semi-rousable. Her pulse is 130 and blood pressure is 100/70. Her breathing is rapid and deep. Teresa’s medical record indicates a history of poorly controlled diabetes and premature coronary artery disease, with a prior myocardial infarction at age 49. She is described as “treatment non-compliant” and is noted to have a “difficult psychosocial situation”.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Anatomy

Lung and pleura

Describe and identify lobes of the lung, bronchopulmonary segments, fissures and surface anatomy of the lung and the fissure

Anatomy Lectures: Respiratory System Anatomy
Control of breathing. Chest wall, diaphragm. The airway.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Identify and describe the pleura, pleural cavity, visceral & parietal pleura, innervation of both layers (intercostal , phrenic, and visceral nerves), surface anatomy of the pleura, Identify Costodiaphragmatic (costophrenic) and costomediastinal recesses and suprapleural membrane

Anatomy Lectures: Respiratory System Anatomy
Control of breathing. Chest wall, diaphragm. The airway.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Understand and describe the blood supply (bronchial artery and vein, pulmonary artery and vein), lymph drainage and nerve supply of the lungs

Anatomy Lectures: Respiratory System Anatomy
Control of breathing. Chest wall, diaphragm. The airway.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Describe the principal bronchi (superior, middle and inferior lobar bronchus), bronchial tree

Anatomy Lectures: Respiratory System Anatomy
Control of breathing. Chest wall, diaphragm. The airway.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Understand the intrapleural pressure and normal mechanics of lung inflation and deflation.

Anatomy Lectures: Respiratory System Anatomy
Control of breathing. Chest wall, diaphragm. The airway.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Understand how haemothorax, pneumothorax, pleural effusion, tension pneumothorax can occur.

Anatomy Lectures: Respiratory System Anatomy
Control of breathing. Chest wall, diaphragm. The airway.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Upper airways

Describe the nose (its walls , nasal septum, nasal lining, concha and meatus) , describe and identify paranasal sinuses (frontal, maxillary, ethmoidal and sphenoidal) , describe the nasoapharynx its walls and lymphoid tissues in the region.

Anatomy Lectures: Respiratory System Anatomy
Control of breathing. Chest wall, diaphragm. The airway.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Describe the larynx its landmark and cartilages (thyroid, cricoid, arytenoid and epiglottis) , divisions (supra glotic, ventricle and infra glotic {subglotic}) , identify the vocal cords (true and false vocal cords), describe the innervation of the larynx (reccurent laryngeal nerve, superior laryngeal nerve)

Anatomy Lectures: Respiratory System Anatomy
Control of breathing. Chest wall, diaphragm. The airway.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Describe the trachea, its anatomic relations and surface markings, bifurcation and carina

Anatomy Lectures: Respiratory System Anatomy
Control of breathing. Chest wall, diaphragm. The airway.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Chest (Thoracic) Wall

Describe surface anatomy and structure of the thoracic wall (ribs, costal cartilages, joints), intercostal spaces and muscles of breathing (intercostal muscles, diaphragm). Describe blood supply and innervations (intercostal neurovascular bundle) of the thoracic wall.

Anatomy Lectures: Respiratory System Anatomy
Control of breathing. Chest wall, diaphragm. The airway.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Describe and understand mechanics of respiration: inspiration (quiet inspiration, vertical diameter, AP diameter, transverse diameter, forced inspiration, expiration (quiet expiration, forced expiration) and lung changes on inspiration and expiration.

Anatomy Lectures: Respiratory System Anatomy
Control of breathing. Chest wall, diaphragm. The airway.
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.

Tutorial Cases

Activities

Introduction to ABGs

Approach to the chest x-ray