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Therapy Part 4 Medical Foundation 4 Musculoskeletal Medicine Part 4 Orthopedics Rheumatology 2.2 Apply biomedical scientific principles fundamental to health care for patients and populations. 2.3 Apply principles of clinical sciences to diagnostic and therapeutic decision-making, clinical problem-solving, and other aspects of evidence-based healthcare 1.4 Make informed decision about diagnostic and therapeutic interventions based on patient information and preferences, up-to-date scientific evidence, and clinical judgment 1.5 Develop and carry out patient management plans Immunotherapy [E02.095.520]