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Basic mechanisms of cellular transformation and the characteristics of malignant cells.
The evolution of clonal populations of genetically abnormal cells, and the types of genes and mutations which cause malignancy.
Examples of genetic pathways of mutation causing cancers to develop, such as CML, retinoblastoma, hereditary breast & ovarian cancer, colorectal cancer.
How to distinguish sporadic cancers from hereditary cancers, and current practices in genetic counseling and clinical management of people at increased risk for hereditary cancers.
Interactions of environmental risk factors and genetic predisposition in common cancers.

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