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Autoimmunity

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Discuss the concept of autoimmunity, the role of the thymus in its development and its role in various disease states.
List the cells that mediate autoimmune conditions.
Describe the roles of the innate and adaptive immune systems as well as the mucosal immune system in the pathogenesis of Celiac disease.
Explain the roles of B- and T-cells in the development of Hashimoto’s thyroiditis and the different theories regarding mechanisms of thyroid injury in this context.
List the autoantigens associated with T1DM.
Outline the contribution of the cellular immune system in the pathogenesis of T1DM.
List autoimmune diseases commonly associated with T1DM.

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