medportal CDB | Taxonomy | Deprecated / Neoplasia - ARCHIVED

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Neoplasia - ARCHIVED

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Week 2

Week 3

Week 4

Week 5

Activities

Farrell Brothers MF4 Neoplasia (Archived)
Tutorial

Matilda Flores MF4 Neoplasia (Archived)
Tutorial

Objectives

Describe a palliative approach to care.
General Objectives

Part 2 / Medical Foundation 2 / Hematology

Upon completion of this case, students will understand the role of inheritance, environment and infectious agents in the development of cancer, using gastric cancer as a model.
Global Objectives

Part 5 / Integration Foundation

Upon completion of this problem, students will be able to describe the pathophysiology of multiple myeloma and its clinical features. Students will be able to describe the importance of apoptosis in the normal tissue and in tumorigenesis, and the limitations of conventional cytoreductive cancer therapies in tumours with defective apoptosis. Students should be able to describe the impact of genetic testing on cancer staging and therapy. Students will be able to describe a palliative approach to care.
Global Objectives

Part 5 / Integration Foundation

Upon completion of this case, the student will have a basic approach to the diagnosis of a new mass lesion, including imaging modalities and diagnostic procedures, as well as an understanding of the multi-disciplinary approach to cancer care and the role of Clinical Practice Guidelines in determining therapy.
Global Objectives

Part 5 / Integration Foundation

Upon completion of this case, students will be able to broadly describe the pathophysiology, clinical manifestations and general approach to management of the hematological malignancies in children. Students should be able to describe the role of genetic testing in the management of children with ALL.
Global Objectives

Part 5 / Integration Foundation

Inspection: draping, position, proper lighting. Inspecting breast and axilla using a model.
General Objectives

Part 5 / Integration Foundation

Palpation: breast and axilla (for mass and lymph nodes) using a model.
General Objectives

Part 5 / Integration Foundation

Lymph Node survey/location (cervical, mental/submental/submandibular, tonsil/adenoid, supraclavicular, axillary, epitrochlear, inguinal, popliteal).
General Objectives

Part 5 / Integration Foundation

Description of lymph nodes.
General Objectives

Part 5 / Integration Foundation

Examination of the spleen: Abdominal examination [inspection for fullness, percussion: (Castell’s method, Traube’s space), palpation of the spleen].
General Objectives

Part 5 / Integration Foundation

Inspection of lesions, palpation of any mass on skin.
General Objectives

Part 5 / Integration Foundation

To know what actions to do when an adverse drug event is suspected.
Activity Objectives

Part 5 / Integration Foundation

To develop a good basic understanding of cancer.
General Objectives

To be able to critically appraise new information as it becomes available both from conventional research as well as the plethora of information from sources such as the internet.
General Objectives

Understand cancer as a disease of dysregulated cellular processes.
General Objectives

What is a tumour suppressor gene?
General Objectives

How can chemicals, radiation and viruses cause cancer?
General Objectives

What is hereditary versus familial cancer?
General Objectives

Are childhood cancers and adult cancers different?
General Objectives

What are the gold standards of cancer diagnosis?
General Objectives

What is a tumour marker and how can it be used?
General Objectives

What is the TNM staging system and what is its relevance?
General Objectives

What are prognostic factors?
General Objectives

What are the goals of surgery in cancer patients?
General Objectives

What is meant by curative, adjuvant and palliative therapy?
General Objectives

What are the predominant classes of systemic therapy?
General Objectives

What is a predictive versus a prognostic factor?
General Objectives

How is radiation used to treat cancers?
General Objectives

Are there long-term consequences of common cancer therapies?
General Objectives

What is the effect of cancer on bone?
General Objectives

What is cancer cachexia?
General Objectives

Understand the role of palliative care in cancer patients.
General Objectives

When should palliative care teams be involved?
General Objectives

What can palliative care teams offer?
General Objectives

Understand the impact of cancer on the population as a whole.
General Objectives

What are the current trends in incidence of cancer and its various types?
General Objectives

What are the reasons behind the current trends in incidence of cancer and its various types?
General Objectives

How are the costs of cancer care impacting the health care system?
General Objectives

To understand some basic principles about the pharmacology of natural health products.
General Objectives

To appreciate the patterns of natural health product use in the population.
General Objectives

Basic mechanisms of cellular transformation and the characteristics of malignant cells.
General Objectives

The evolution of clonal populations of genetically abnormal cells, and the types of genes and mutations which cause malignancy.
General Objectives

Examples of genetic pathways of mutation causing cancers to develop, such as CML, retinoblastoma, hereditary breast & ovarian cancer, colorectal cancer.
General Objectives

How to distinguish sporadic cancers from hereditary cancers, and current practices in genetic counseling and clinical management of people at increased risk for hereditary cancers.
General Objectives

Interactions of environmental risk factors and genetic predisposition in common cancers.
General Objectives

Upon completion of this case, students will be able to describe the role of oncogenes in the generation of cancers and be able to describe the importance of pathology in the diagnosis and management of cancer.
Global Objectives

Upon completion of this case, students will apply their understanding of hereditary cancer to the clinical management and psychosocial issues of a family with hereditary breast cancer.
Global Objectives

Upon completion of this case, students will be able to contrast sporadic and hereditary patho-genetic mechanisms in colorectal cancer and discuss the role of adjuvant chemotherapy and surveillance after surgery.
Global Objectives

Upon completion of this case, students will be able to define palliative care and describe the role of palliative care in the setting of complex cancer patients.
Global Objectives

Describe how sporadic and hereditary cancers arise from normal tissues.
General Objectives

Distinguish sporadic and hereditary presentations of cancer.
General Objectives

Identify which members of a family might be at increased risk for hereditary cancer.
General Objectives

Describe current protocols and practices for the management of common hereditary cancers, understanding how the principles of cancer screening apply to these early detection and prevention programs.
General Objectives

Understand how the characterization of molecular changes in cancers and tumours can lead to the development of targeted therapies and improve treatment outcomes.
General Objectives

Explain the risks, benefits and limitation of genetic testing for hereditary cancer.
General Objectives

Be aware of genetics techniques used for cancer diagnosis.
General Objectives

Upon completion of this case, student will be able to describe the role of viruses in oncogenesis, and the potential role of vaccines in cancer prevention. Students will be able to describe the characteristics of an effective population screening program and the mechanisms by which screening can reduce the burden of cancer. Students will be able to describe broadly the differences in the incidence of common cancers in Canada compared to worldwide.
Global Objectives

To appreciate the pattern of natural health product use in the population.
Activity Objectives

To be aware of therapeutic benefits and risks associated with natural health products.
Activity Objectives

To identify resources for obtaining reliable information about natural health products.
Activity Objectives

Describe palliative care.
Activity Objectives

Describe elements of good pain history.
Activity Objectives

Assess pain severity using validated tools.
Activity Objectives

Identify causes of acute and chronic cancer pain.
Activity Objectives

Differentiate nociceptive versus neuropathic pain.
Activity Objectives

Pharmacotherapy: multimodal analgesia.
Activity Objectives

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