Ron Chen (Part 2) MF4 Neurology
					Activity
Tutorial
					
											Tutorial
Remember back in MF1...
Ron Chen is a 25 year old computer sciences graduate student who had been previously well. Three weeks ago he suffered a viral gastroenteritis from which he has recovered. Over the past week, he has noticed increasing weakness of his limbs, starting with his legs, and progressing to involve his arms. He reports he has experienced patchy areas of sensory loss, symmetrically (glove and stocking distribution). He has also noticed occasional clumsy speech and facial weakness. He is admitted to the hospital (medical ward) with a diagnosis of Guillain Barré syndrome.
You see him in followup 12 months later. After spending 3 weeks in hospital, 4 weeks in a rehabilitation center and then having physiotherapy for the rest of the year, Ron is almost completely back to normal.  He still reports some weakness with extension of his toes on the right, but this does not impair his functioning.  During his visit, he asks if he will ever get the strength back in his toes, and whether this could happen again
										
											Curriculum Block
Medical Foundation 4 / Neuroscience / Part 4 / Week 3 
					
                     - Indicates most relevant
					
											Objectives
General Objectives
- Discuss the following electrophysiological concepts surrounding excitable cells: 1) resting potentials, 2) post-synaptic potentials, 3) action potential generation and propagation in unmyelinated and myelinated neurons.
- Explain the clinical presentation and pathophysiology of length dependant neuropathies.
Global Objectives
										
											Assessments
End-Unit Tutorial Assessment
Mini Concept Application Exercise (CAE)
						
											Tags
Basic Sciences
									
										Physiology		
											
										
									Curriculum Block
									
										Medical Foundation 4		
											
										
									
									
										Neuroscience		
											
										
									
									
										Part 4		
											
										
									
									
										Week 3		
											
										
									Curriculum Week
									
										Part 4		
											
										
									
									
										Week 7		
											
										
									Discipline
									
										Neurology		
											
										
									Longitudinal Discipline
									
										Immunology		
											
										
									MCC Presentations
									
										Weakness (not caused by Cerebrovascular Accident)		
											
										
									McMaster Program Competencies
									
										1.1 Gather essential and accurate information about patients and their health through history-taking, physical examination, and the use of laboratory data, imaging, and other tests.		
											
										
									
									
										1.3 Interpret laboratory data, imaging studies, and other tests required for the area of practice		
											
										
									
									
										1.4 Make informed decision about diagnostic and therapeutic interventions based on patient information and preferences, up-to-date scientific evidence, and clinical judgment		
											
										
									
									
										1.5 Develop and carry out patient management plans		
											
										
									
									
										2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.		
											
										
									
									
										2.3 Apply principles of clinical sciences to diagnostic and therapeutic decision-making, clinical problem-solving, and other aspects of evidence-based healthcare		
											
										
									MeSH
									
										Action Potentials [G04.580.100]		
											
										
									
									
										Autoimmune Diseases of the Nervous System [C10.114]		
											
										
									
									
										Electrophysiological Processes [G07.265.337]		
											
										
									
									
										Guillain-Barre Syndrome [C10.114.750.100]		
											
										
									
									
										Muscle Weakness [C10.597.613.593]		
											
										
									
									
										Myelin Sheath [A08.637.600.500]		
											
										
									
									
										Neural Conduction [G11.561.600.620]		
											
										
									
									
										Peripheral Nervous System Diseases [C10.668.829]		
											
										
									
									
										Polyradiculoneuropathy [C10.114.750]		
											
										
									
									
										Synaptic Potentials [G07.265.337.900.750]		
											
										
																		