Shelley Clerke MF4 Neurology
					Activity
Tutorial
					
											Tutorial
Shelley Clerke is a 72-year-old woman who has had Parkinson's disease for over 10 years. Initially the disorder presented with tremor on her right side. She has been managed by her family doctor and local neurologist. Over the years her medications have been adjusted and new medications added to control her symptoms. More recently, she is experiencing increasing difficulty with activities such as eating and signing her name due to the tremor. Two years ago she started using a rollator walker when her balance and overall mobility made it difficult for her to ambulate in the community with just a cane. Today she has an appointment with her neurologist. The neurologist notes the increase in tremor and her poor overall mobility compared to when he last reviewed her 6 months ago. Her Parkinson medications include: Levodopa/carbidopa 250/25 mg QID, entacapone 200 mg QID, ropinirole 3 mg QID, and amantidine 100 mg BID. On examination she has an obvious and severe right-sided resting tremor that does not completely stop when she raises her arms. She has difficulty getting out of the chair and on to the examination table.
										
											Curriculum Block
Medical Foundation 4 / Neuroscience / Part 4 / Week 3 
					
                     - Indicates most relevant
					
											Objectives
General Objectives
- Discuss the anatomy, physiological connections, and neurochemistry of basal ganglia.
- Describe the role of the basal ganglia in the control of movement.
- Recognize signs of basal ganglia dysfunction.
- Explain the pathophysiology and clinical presentation of Parkinsonism.
- Describe the mechanism of action for the drugs used in the treatment of Parkinsonism.
Global Objectives
										
											Assessments
Mid-Unit Tutorial Assessment
End-Unit Tutorial Assessment
Mini Concept Application Exercise (CAE)
						
											Tags
AFMC National Clinical Skills
									
										Neurological Examination		
											
										
									Basic Sciences
									
										Anatomy		
											
										
									
									
										Biochemistry		
											
										
									
									
										Genetics		
											
										
									
									
										Pharmacology		
											
										
									
									
										Physiology		
											
										
									Cohort Year
									
										2010		
											
										
									Curriculum Block
									
										Medical Foundation 4		
											
										
									
									
										Neuroscience		
											
										
									
									
										Part 4		
											
										
									
									
										Week 3		
											
										
									Curriculum Week
									
										Part 4		
											
										
									
									
										Week 7		
											
										
									Discipline
									
										Genetics		
											
										
									
									
										Neurology		
											
										
									Longitudinal Discipline
									
										Genetics		
											
										
									MCC Presentations
									
										Genetic Concerns		
											
										
									
									
										Movement Disorders, Involuntary / Tic Disorders		
											
										
									
									
										Weakness (not caused by Cerebrovascular Accident)		
											
										
									McMaster Program Competencies
									
										1.1 Gather essential and accurate information about patients and their health through history-taking, physical examination, and the use of laboratory data, imaging, and other tests.		
											
										
									
									
										1.3 Interpret laboratory data, imaging studies, and other tests required for the area of practice		
											
										
									
									
										1.4 Make informed decision about diagnostic and therapeutic interventions based on patient information and preferences, up-to-date scientific evidence, and clinical judgment		
											
										
									
									
										1.5 Develop and carry out patient management plans		
											
										
									
									
										2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.		
											
										
									
									
										2.3 Apply principles of clinical sciences to diagnostic and therapeutic decision-making, clinical problem-solving, and other aspects of evidence-based healthcare		
											
										
									MeSH
									
										 Antiparkinson Agents [D27.505.954.427.090.050]    		
											
										
									
									
										  Basal Ganglia Diseases [C10.228.140.079]		
											
										
									
									
										 Dyskinesias [C10.597.350]		
											
										
									
									
										Aged [M01.060.116.100]		
											
										
									
									
										Basal Ganglia [A08.186.211.730.885.105]		
											
										
									
									
										Brain Diseases [C10.228.140]		
											
										
									
									
										Carbidopa [D02.092.311.200.538.200]					
											
										
									
									
										Chorea [C10.597.350.250]		
											
										
									
									
										Chronic Disease [C23.550.291.500]		
											
										
									
									
										Diagnostic Techniques and Procedures [E01.370]		
											
										
									
									
										Direct-To-Consumer Screening and Testing [E01.370.398]		
											
										
									
									
										Disease Management [N04.590.607]		
											
										
									
									
										Gait [E01.370.600.250]		
											
										
									
									
										Genetic Testing [E01.370.225.562]		
											
										
									
									
										Genetic Testing [E05.393.435] 		
											
										
									
									
										Genetic Testing [N02.421.308.430]		
											
										
									
									
										Genetics [H01.158.273.343]		
											
										
									
									
										Hyperkinesis [C10.597.350.350]		
											
										
									
									
										Hypokinesia [C10.597.350.400]		
											
										
									
									
										Levodopa [D02.092.311.200.480]				
											
										
									
									
										Movement Disorders [C10.228.662]		
											
										
									
									
										Movement [G11.427.590.530]		
											
										
									
									
										Muscle Rigidity [C05.651.504]		
											
										
									
									
										Neurodegenerative Diseases [C10.574]		
											
										
									
									
										Neuromuscular Manifestations [C10.597.613]		
											
										
									
									
										 Parkinson Disease [C10.228.140.079.862.500]		
											
										
									
									
										Parkinsonian Disorders [C10.228.140.079.862]		
											
										
									
									
										Preventative Health Services [N02.421.143.827]		
											
										
									
									
										Tremor [C10.597.350.850]		
											
										
																		