Autoimmunity
Activity
Active Large Group Session
Active Large Group Session
Curriculum Block
Gastroenterology and Nutrition / Medical Foundation 3 / Part 3 / Week 2
- Indicates most relevant
Objectives
Activity Objectives
- Discuss the concept of autoimmunity, the role of the thymus in its development and its role in various disease states.
- List the cells that mediate autoimmune conditions.
- Describe the roles of the innate and adaptive immune systems as well as the mucosal immune system in the pathogenesis of Celiac disease.
- Explain the roles of B- and T-cells in the development of Hashimoto’s thyroiditis and the different theories regarding mechanisms of thyroid injury in this context.
- List the autoantigens associated with T1DM.
- Outline the contribution of the cellular immune system in the pathogenesis of T1DM.
- List autoimmune diseases commonly associated with T1DM.
Assessments
Concept Application Exercise (CAE)
Tags
Basic Sciences
Immunology
Curriculum Block
Gastroenterology and Nutrition
Medical Foundation 3
Part 3
Week 2
Curriculum Week
Part 3
Week 2
Discipline
Allergy and Immunology
Endocrinology
MCC Presentations
Diabetes Mellitus
McMaster Program Competencies
1.3 Interpret laboratory data, imaging studies, and other tests required for the area of practice
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.
2.4 Apply principles of epidemiological sciences to the identification of health problems, risk factors, treatment strategies, resource allocation, and disease prevention/health promotion efforts for patients and populations
MeSH
Adaptive Immunity [G12.450.050]
Autoimmunity [G12.450.192]
Celiac Disease [C06.405.469.637.250]
Celiac Disease [C18.452.603.250]
Diabetes Complications [C19.246.099]
Diabetes Mellitus [C19.246]
Diabetes Mellitus, Type 1 [C19.246.267]
Immunity [G12.450]
Thyroid Diseases [C19.874]
Thyroiditis [C19.874.871]