Philippe LaCologne IF Host Defence and Neoplasia
Activity
Tutorial
Mr. Lacologne is a 41 year old man who had a stage II colon cancer resected 3 years prior. He had his annual CT scan, and there was a 3 cm hypoechoic lesion in segment 6. His surgeon referred him to a liver Surgeon and Medical Oncologist. The surgeon explained that this is likely recurrent disease from his colon cancer, and recommended chemotherapy neo-adjuvantly and after surgery. He was started on FOLFOX chemotherapy for 6 cycles, subsequent CT and MRI of his liver showed a partial response to chemotherapy. He underwent a left hepatic lobectomy, and following recovery completed an additional 6 cycles of FOLFOX. Two years later subsequent lung lesions are identified in multiple lobes bilaterally. He returns to the Medical Oncologist, and is recommended to start chemotherapy (FOLFIRI/bevacizumab). He asks why surgery is not an option now, and said he heard on the internet that that this bevacizumab drug can cure cancer.

Curriculum Block

Host Defense and Neoplasia / Integration Foundation / Part 5 / Week 3
- Indicates most relevant

Objectives

General Objectives
Global Objectives

Assessments

Mid-Unit Tutorial Assessment
Concept Application Exercise (CAE)
End-Unit Tutorial Assessment

Tags

Basic Sciences
Genetics
Curriculum Block
Host Defense and Neoplasia Integration Foundation Part 5 Week 3
Curriculum Week
IF Week 3
Discipline
Genetics Medical Oncology
McMaster Program Competencies
2.2 Apply biomedical scientific principles fundamental to health care for patients and populations.
MeSH
Adenocarcinoma [C04.557.470.200.025] Angiogenesis Inhibitors [D27.505.696.377.077.099] Antineoplastic Agents [D27.505.954.248] Antineoplastic Agents, Immunological [D27.505.954.248.384] Chemotherapy, Adjuvant [E02.186.170] Colonic Neoplasms [C04.588.274.476.411.307.180] Genetic Counseling [H01.158.273.343.315.384] Genetic Counseling [N02.421.308.400] Neoplasm Metastasis [C04.697.650] Neoplasm Staging [E01.370.550] Tropism [G07.345.249.845]

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